Can an Anti-Gravity treadmill or supplements beat knee arthritis pain?

NCT ID NCT07399743

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two add-on treatments for knee osteoarthritis in overweight women: walking on an anti-gravity treadmill that unloads the joints, or taking alpha-lipoic acid and omega-3 supplements. Both aim to reduce pain and improve function better than standard physical therapy alone. The trial will enroll 160 women aged 20-45 with mild to moderate knee osteoarthritis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Alpha-lipoic acid and omega-3 fatty acids
What this could lead to
If successful, this could point to a more effective combination of treatments to reduce pain and improve mobility in overweight women with knee osteoarthritis.
What could go wrong
This is a Phase 3 trial, but it has not yet started recruiting. The results may not apply to all people with knee osteoarthritis, and the supplements or therapy may not provide significant benefits over standard physical therapy.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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