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Hands-On relief: which therapy eases knee arthritis pain best?

NCT ID NCT07710404

Symptom relief Sponsor: University of Faisalabad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study compares two hands-on therapy techniques—joint distraction and passive end-range overpressure—for people with knee osteoarthritis. Participants, aged 40 to 60 with moderate knee pain, receive one of the two treatments over four weeks. The goal is to see which approach better reduces pain, improves knee movement, and enhances daily function and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
joint distraction and passive joint end-range overpressure (manual therapy techniques)
What this could lead to
If one technique proves more effective, it could offer a simple, non-drug way to ease pain and improve mobility in people with knee osteoarthritis.
What could go wrong
This is a small, early-stage trial with only 26 participants, so results may not apply to everyone. The techniques are manual and depend on the therapist's skill.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

26 people

The number who actually took part.

Started

Dec 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 59 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Patients diagnosed with Grade 2 or Grade 3 Knee Osteoarthritis. * A Kellgren-Lawrence Grade (KLG) of at least 2. * Age between 40-60 years. * Knee pain for at least 6 months. * A minimum pain score of 3 on the Visual Analogue Scale (VAS). Exclusion Criteria * Acute inflammation. * Total Knee Replacement (TKR) surgery. * Any lumbar spine disease (disc herniation or lumbar stenosis). * Intra-articular injection. * Recent tibia or femur fracture. * Any systemic inflammatory arthritic condition or neurological condition (e.g., rheumatoid arthritis or stroke).

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee osteogenesis imperfecta Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Joint distraction Osteoarthritis Osteogenesis

Contacts and locations

Locations

  • The university of Faisalabad

    Faisalābad, Punjab Province, 3800, Pakistan

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