Which shot works best for aching knees? new study to find out

NCT ID NCT07243392

Not yet recruiting Symptom relief Sponsor: Lincoln University College Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will compare three common injection treatments for knee osteoarthritis: steroids, dextrose prolotherapy, and platelet-rich plasma (PRP). Seventy-two adults aged 40 to 80 with moderate to severe knee arthritis will receive one of the three injections. Researchers will measure pain and function over time to see which option provides the best and longest-lasting relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Steroid injection, dextrose prolotherapy, or platelet-rich plasma (PRP) injection
What this could lead to: If successful, this study could show which injection works best for long-term knee pain relief and function in osteoarthritis, helping guide treatment choices.
What could go wrong: This is a small, early-stage comparative study with no blinding, so results may be biased. It is not yet recruiting, and individual responses to injections vary widely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRITIS

Contacts and locations

Locations

Health Sciences

Lahore, Punjab Province, 64200, Pakistan

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