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Same knee pain, different mobility: scientists probe the gap

NCT ID NCT07869680

Knowledge-focused Sponsor: Mardin Artuklu University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 09, 2026 · Last updated Oct 09, 2026

Summary

People with knee osteoarthritis often report similar pain levels but differ widely in how well they walk, stand from a chair, and manage daily tasks. Researchers at Mardin Artuklu University are studying 120 adults with moderate knee pain to find which clinical factors explain those differences. Participants complete questionnaires on function, central sensitization symptoms, and physical activity, plus walking and chair-stand tests. The study assigns no treatment; it aims to understand functional capacity, not to test a therapy.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers identify which factors track with better function, that could help doctors tailor exercise or pain care for people with knee osteoarthritis.
What could go wrong
This is a single-visit observational study with 120 participants, so it can show links but not prove cause. Findings may not apply to people with milder or more severe knee arthritis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adults attending the Physical Medicine and Rehabilitation outpatient clinic of Mardin Training and Research Hospital with clinical and radiographic knee osteoarthritis. Only patients with Kellgren-Lawrence grade 2 or 3 disease and similar moderate knee pain severity will be included. No healthy control group will be enrolled.

Ages

40 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 40-75 years * Clinical and radiographic diagnosis of knee osteoarthritis * Kellgren-Lawrence grade 2 or 3 knee osteoarthritis * Knee pain lasting at least 3 months * Average knee pain intensity during the previous week between 4 and 6 on a 0-10 visual analog scale * Ability to provide written informed consent Exclusion Criteria: * Kellgren-Lawrence grade 1 or 4 knee osteoarthritis * Inflammatory rheumatic disease * History of knee surgery or intra-articular knee injection within the previous 6 months * Neurological disease that substantially affects knee function * Severe cardiopulmonary disease that prevents walking or performance testing * Cognitive impairment that prevents participation in the assessment procedures * For participants with bilateral knee osteoarthritis, assessments will be performed on the more painful knee.

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Conditions

The condition(s) this trial relates to.

Motor Activity osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Mardin Training and Research Hospital

    RECRUITING

    Mardin, 47100, Turkey (Türkiye)

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