Can a simple blood or joint fluid test predict knee arthritis outcomes?

NCT ID NCT06600958

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will follow 300 people with knee osteoarthritis or chronic inflammatory arthritis for up to 10 years. Researchers will collect blood, joint fluid, and platelet-rich plasma samples to look for biomarkers linked to pain, joint damage, and the need for knee replacement. The goal is to better understand why some people worsen quickly and why some treatments work better for certain patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors predict which knee osteoarthritis patients will worsen and who will respond best to treatments like steroid injections.

What could go wrong

This is an observational study, not a treatment trial. It may not find clear biomarkers, and results may take years to apply in practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee rheumatic disorder rheumatic fever rheumatoid arthritis spondyloarthropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Henri Mondor

    RECRUITING

    Créteil, 94000, France