Can a simple blood or joint fluid test predict knee arthritis outcomes?

NCT ID NCT06600958

Recruiting now Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will follow 300 people with knee osteoarthritis or chronic inflammatory arthritis for up to 10 years. Researchers will collect blood, joint fluid, and platelet-rich plasma samples to look for biomarkers linked to pain, joint damage, and the need for knee replacement. The goal is to better understand why some people worsen quickly and why some treatments work better for certain patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict which knee osteoarthritis patients will worsen and who will respond best to treatments like steroid injections.
What could go wrong: This is an observational study, not a treatment trial. It may not find clear biomarkers, and results may take years to apply in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee rheumatic disorder rheumatic fever rheumatoid arthritis spondyloarthropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC INFLAMMATORY RHEUMATISM KNEE OSTEOARTHRITIS

Contacts and locations

Locations

Henri Mondor
RECRUITING

Créteil, 94000, France

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