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Which knee exercise works better? new study compares eccentric vs concentric moves

NCT ID NCT07460466

Symptom relief Sponsor: Indonesia University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two types of leg exercises in 24 women with knee osteoarthritis to see which better improves muscle strength, knee movement, and daily function. Participants did either eccentric (lengthening) or concentric (shortening) quadriceps exercises three times a week for six weeks. The goal is to help doctors recommend the best exercise for knee pain and stiffness.

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

24 people

The number who actually took part.

Started

Jul 2024

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 59 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female participants aged 40-59 years * Diagnosed with unilateral or bilateral knee osteoarthritis based on American College of Rheumatology (ACR) criteria and Kellgren-Lawrence grade II-III * Knee pain lasting more than 3 months with Numeric Rating Scale (NRS) score 1-3 * Limited knee flexion range of motion Exclusion Criteria: * History of unstable cardiovascular, respiratory, or metabolic disease * Knee joint instability due to cruciate or collateral ligament laxity or meniscal injury * Previous knee surgery * History of knee intra-articular injection within the last 3 months * Cognitive impairment (Montreal Cognitive Assessment Indonesian Version \[MoCA-Ina\] score \< 26) * Clinical signs of tendinopathy characterized by pain during active knee extension (open or closed kinetic chain) * Balance disorders

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis

Contacts and locations

Locations

  • Department of Physical Medicine and Rehabilitation

    Jakarta, DKI Jakarta, 10430, Indonesia

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Other studies related to the condition(s) this trial covers.