Knee implant showdown: which one works better?
NCT ID NCT01064063
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared two types of knee implants—the Vanguard Cruciate Retaining and the AGC Total Condylar—in 150 patients with knee arthritis. The goal was to see which implant provides better pain relief and function after knee replacement surgery. Patients were followed for several years to measure knee scores and success rates.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vanguard Cruciate Retaining knee implant and AGC total condylar knee implant
What this could lead to
If one implant proves better, it could lead to improved knee replacement outcomes for patients with arthritis.
What could go wrong
This is a completed trial with 150 participants, so results are limited to this group and may not apply to all patients. Both implants are already in use, so no major breakthrough is expected.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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East Sussex Hospital NHS Trust
Saint Leonards-on-Sea, East Sussex, TN37 7RD, United Kingdom