Hormone injection reveals how long COVID affects the brain

NCT ID NCT07224490

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study gives a single dose of kisspeptin, a natural hormone, to 40 people with and without Long COVID. Researchers will take frequent blood samples to measure how the brain's reproductive hormone system responds. The goal is to understand if Long COVID disrupts this system, which could lead to better insights into related health issues.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Kisspeptin (a natural hormone given as a single injection)

What this could lead to

If successful, this could help explain how Long COVID affects the brain's reproductive hormone system, pointing toward future treatments for related symptoms.

What could go wrong

This is a very early Phase 1 study with only 40 participants, so results may not apply broadly. It is designed to measure hormone responses, not to test a treatment, so direct benefits are unlikely.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

COVID-19 long COVID-19 Nerve Degeneration neurodegenerative disease post-COVID-19 disorder reproductive system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••