Which antibiotic combo is kinder to kidneys? new study aims to find out

NCT ID NCT06954129

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at two common antibiotic combinations given to hospitalized adults with infections: vancomycin plus piperacillin-tazobactam, or vancomycin plus cefepime. The goal is to see if one is less likely to cause kidney injury than the other, using more sensitive markers than the standard blood test. About 750 participants will be followed for 5 days to measure changes in kidney function. The results will help doctors choose safer treatments.

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Conditions

The condition(s) this trial relates to.

acute kidney injury infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pennsylvania Health System

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States