Could a Low-Carb diet and diabetes drug help fight brain cancer?

NCT ID NCT04691960

First seen Jan 10, 2026 · Last updated May 08, 2026 · Updated 15 times

Summary

This study tests whether a high-fat, low-carbohydrate (ketogenic) diet combined with the diabetes drug metformin is safe and tolerable for people with glioblastoma, an aggressive brain cancer. The idea is that lowering blood sugar may slow tumor growth. Participants work with a nutritionist to prepare their own meals and continue treatment as long as they benefit without serious side effects.

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Contacts and locations

Locations

  • Columbia University

    New York, New York, 10032, United States

  • Weill Cornell Medicine

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.