Could a keto diet supercharge brain therapy for depression?

NCT ID NCT07376018

First seen Feb 01, 2026 · Last updated May 08, 2026 · Updated 16 times

Summary

This study tests whether adding a low-carb ketogenic diet to a personalized brain stimulation treatment (iTBS) can better reduce depression symptoms in adults with treatment-resistant depression. Sixty participants will follow either a ketogenic diet or a standard healthy diet for 12 weeks, with brain stimulation given after a 3-week diet lead-in. The goal is to see if the diet makes the brain therapy more effective and is safe and practical to follow.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M4N 3M5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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