Could earlier ketamine stop seizures faster?
NCT ID NCT07177235
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether giving the drug ketamine earlier, along with midazolam, can stop prolonged seizures faster in adults. Researchers will compare early versus late ketamine timing in 50 patients with refractory status epilepticus. The goal is to see if earlier use shortens seizure duration.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ketamine and midazolam
- What this could lead to
- If successful, this could show that earlier use of ketamine helps stop prolonged seizures faster, potentially improving outcomes for patients.
- What could go wrong
- This is a small pilot study with only 50 participants, so results may not apply broadly. The timing difference is modest, and the study hasn't started yet.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.