Anesthetic gas may tame stubborn seizures when other drugs fail

NCT ID NCT05830864

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study reviewed medical records of 66 adults in intensive care who received the anesthetic gas isoflurane for severe seizures that didn't respond to standard treatments. Researchers wanted to see how often isoflurane stopped the seizures or led to full awakening. The goal is to find a backup option for these life-threatening situations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Isoflurane (an inhaled anesthetic)

What this could lead to

If results are positive, isoflurane could become a reliable option to stop prolonged seizures when other treatments fail.

What could go wrong

This is a small, retrospective review (66 patients), not a controlled trial, so results may not prove cause and effect. Isoflurane is an anesthetic with risks like low blood pressure and breathing problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

new-onset refractory status epilepticus Status Epilepticus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CH Toulon - Sainte Musse

    Toulon, 83000, France

  • CHU Brest

    Brest, 29200, France

  • Ch Bethune Beuvry

    Beuvry, 62660, France

  • GH Sud Ile de France, Hôpital de Melun-Sénart

    Melun, 77000, France