Anesthetic gas may tame stubborn seizures when other drugs fail
NCT ID NCT05830864
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study reviewed medical records of 66 adults in intensive care who received the anesthetic gas isoflurane for severe seizures that didn't respond to standard treatments. Researchers wanted to see how often isoflurane stopped the seizures or led to full awakening. The goal is to find a backup option for these life-threatening situations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Isoflurane (an inhaled anesthetic)
- What this could lead to
- If results are positive, isoflurane could become a reliable option to stop prolonged seizures when other treatments fail.
- What could go wrong
- This is a small, retrospective review (66 patients), not a controlled trial, so results may not prove cause and effect. Isoflurane is an anesthetic with risks like low blood pressure and breathing problems.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CH Toulon - Sainte Musse
Toulon, 83000, France
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CHU Brest
Brest, 29200, France
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Ch Bethune Beuvry
Beuvry, 62660, France
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GH Sud Ile de France, Hôpital de Melun-Sénart
Melun, 77000, France
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