Could a quick ketamine infusion lift depression in ICU patients?

NCT ID NCT07639359

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a low dose of ketamine, given as an IV infusion, can quickly improve depressive symptoms in adults who have been in the intensive care unit (ICU) for at least 6 days. About 50 participants will receive either ketamine or a placebo on two days in a row. Researchers will check mood changes and safety over the next month.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Italiano de Buenos Aires - Sede Central

    RECRUITING

    Buenos Aires, Buenos Aires, Argentina

  • Mayo Clinic

    RECRUITING

    Jacksonville, Florida, 32224, United States

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