Long-Term study aims to unlock mystery of joint hypermobility and chronic illness

NCT ID NCT07657507

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will follow 100 health science students for at least 10 years to understand why some people with very flexible joints (hypermobility) develop chronic pain, fatigue, and other health issues while others do not. Researchers will measure balance, heart rate, and quality of life at the start and track changes over time. The goal is to identify factors that trigger the transition from harmless joint flexibility to a condition called Hypermobility Spectrum Disorder.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help identify early warning signs for who might develop chronic pain and other health issues from joint hypermobility.

What could go wrong

This is an observational study, not a treatment trial. It will take at least 10 years to follow participants, and results may not apply to the general population.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Ehlers-Danlos syndrome, hypermobility type hypermobility spectrum disorder mast cell activation syndrome postural orthostatic tachycardia syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clarkson University, Lewis School of Health & Life Sciences

    Potsdam, New York, 13699, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••