Could a gut hormone boost islet transplants and free type 1 diabetes patients from insulin shots?
NCT ID NCT03746769
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a natural gut hormone called gastrin to islet cell transplants can help people with hard-to-control type 1 diabetes produce their own insulin and stabilize blood sugar. About 20 adults aged 18-68 with unstable type 1 diabetes will receive donor islet cells plus gastrin. The goal is to see if they can stop insulin injections and avoid dangerous low blood sugar episodes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
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