Could a gut hormone boost islet transplants and free type 1 diabetes patients from insulin shots?

NCT ID NCT03746769

First seen Feb 28, 2026 · Last updated May 11, 2026 · Updated 11 times

Summary

This study tests whether adding a natural gut hormone called gastrin to islet cell transplants can help people with hard-to-control type 1 diabetes produce their own insulin and improve blood sugar. About 20 adults aged 18-68 with unstable blood sugar will receive donor islet cells plus gastrin. The goal is to see if they can stop insulin injections and avoid dangerous low blood sugar episodes.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact

Conditions

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