Could donor islet cells free diabetics from insulin after kidney transplant?

NCT ID NCT01241864

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether transplanting insulin-producing islet cells from deceased donors can help people with type 1 diabetes who have already received a kidney transplant. The goal is to achieve safe blood sugar levels without insulin shots. Ten participants will receive the cells via a vein in the liver and must take immunosuppressant drugs as long as the cells work.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Allogenic islet cells (donor pancreas cells) plus immunosuppressant drugs

What this could lead to

If successful, this could help people with type 1 diabetes who have had a kidney transplant achieve near-normal blood sugar without insulin shots, reducing complications.

What could go wrong

This is a very small early-phase trial (10 people) and requires lifelong immunosuppression, which carries risks like infection and organ damage. It may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DIABETES MELLITUS, TYPE 1 are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus type 1 diabetes mellitus 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact