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Tooth rinse showdown: which cleans better before a root repair?

NCT ID NCT06757660

Symptom relief Sponsor: Minia University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two different irrigation (rinsing) methods used just before repairing a hole in a tooth's root (furcation perforation). Forty adults with this type of tooth damage received either a chitosan or sodium hypochlorite rinse. Researchers measured pain levels and healing over 9 months to see which approach worked better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
chitosan and sodium hypochlorite (NaOCl) irrigation solutions
What this could lead to
If successful, this could point toward a better way to clean tooth perforations before repair, reducing pain and improving healing.
What could go wrong
This is a small, completed trial with only 40 participants, so results may not apply to everyone. The benefit over standard care is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Oct 2023

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with old furcation perforation of mandibular molar. * Size of perforation should be of average 1 to 2 mm. * Period till treatment should be done within one month. * Presence of polyp at the site of perforation is required in this study. Exclusion Criteria: * Teeth in need for post retained restoration. * Immunocompromised patients. * Pregnant women and smokers. * Patients with a history of antibiotic or analgesics intake within the few days before the intervention and cases with previously initiated endodontic treatment.

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Conditions

The condition(s) this trial relates to.

Furcation Defects

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Furcation defects

Contacts and locations

Locations

  • Minia University, Faculty of Dentistry

    Minya, Egypt

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