Animal membranes battle to save molars: which works best?

NCT ID NCT06681532

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two different membranes (one from cow pericardium, one from cow collagen) used with a bone graft to treat a specific type of bone loss between the roots of lower molars. Twenty patients with class II furcation defects will receive one of the two treatments, and their gum health and bone levels will be measured at 3 and 6 months. The goal is to see which membrane leads to better bone and gum attachment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
bovine bone graft mixed with concentrated growth factor, covered with either native collagen membrane or bovine pericardium membrane
What this could lead to
If successful, this could point toward a better way to repair bone loss around the roots of lower molars, potentially saving teeth that might otherwise be lost.
What could go wrong
This is a very small, early-stage trial with only 20 patients, so results may not apply to everyone. The membranes are from animal tissue, which could cause allergic reactions or rejection in some people.

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Conditions

The condition(s) this trial relates to.

Furcation Defects

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of dentistry , Mansoura university

    Al Mansurah, Dakahlia Governorate, 35516, Egypt

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