Gum repair breakthrough? new combo treatment shows promise for Tooth-Saving surgery
NCT ID NCT07042204
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study tested whether using a patient's own blood concentrate (ePRF) alone or mixed with bioactive glass nanoparticles can help repair bone defects in gum disease. Thirty adults with grade II furcation defects (bone loss between tooth roots) received one of three surgical treatments. The main goal was to measure bone fill using 3D X-rays.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- extended platelet-rich fibrin (ePRF) and bioactive glass nanoparticles
- What this could lead to
- If successful, this could point toward a better way to repair bone loss in gum disease, potentially improving tooth retention.
- What could go wrong
- This is a small, early-stage study with only 30 participants, so results may not apply widely. The treatments are surgical procedures, and outcomes depend on individual healing.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Mansoura University
Al Mansurah, 35516, Egypt
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Other studies related to the condition(s) this trial covers.
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