Parkinson's patients get brain transplants of their own cells

NCT ID NCT06422208

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-stage trial tests whether transplanting dopamine neurons made from a patient's own stem cells into the brain is safe for Parkinson's disease. Six people aged 55 to 80 with Parkinson's for at least 5 years will receive the cells in a single surgery. The main goal is to check for side effects, but researchers will also monitor motor function changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

autologous iPSC-derived dopamine neurons

What this could lead to

If successful, this could point toward a new way to replace lost brain cells and improve motor function in Parkinson's disease.

What could go wrong

This is a very early, small safety trial with only 6 people. The procedure involves brain surgery, which carries risks like infection or bleeding. It may not improve symptoms.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham & Women's Hospital

    Boston, Massachusetts, 02215, United States