New vaccine aims to protect african children from deadly salmonella

NCT ID NCT06213506

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new vaccine (iNTS-GMMA) designed to prevent severe Salmonella infections caused by two common strains. Researchers are giving the vaccine to healthy adults, children, and infants in Ghana to check if it is safe and triggers a strong immune response. The ultimate goal is to protect young infants, starting from 6 weeks of age, who are most at risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
iNTS-GMMA vaccine (a vaccine against invasive nontyphoidal Salmonella)
What this could lead to
If successful, this could lead to a vaccine that protects African infants and children from severe, often deadly Salmonella infections.
What could go wrong
This is an early Phase 2 trial with only 215 participants, so the vaccine may not prove safe or effective enough for wider use. Side effects like pain, fever, or allergic reactions are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SALMONELLA INFECTIONS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • GSK Investigational Site

    Kumasi, Ghana

More trials for these conditions

Other studies related to the condition(s) this trial covers.