New combo aims to control prostate cancer without sacrificing erections

NCT ID NCT04025372

First seen Jan 04, 2026 · Last updated May 15, 2026 · Updated 17 times

Summary

This study compares a new hormone therapy (darolutamide) plus radiation against standard hormone therapy plus radiation for men with intermediate-risk prostate cancer. The goal is to see if the new approach works just as well at controlling the cancer while also helping men keep their erectile function. About 234 men are taking part in this phase 2 trial.

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Contacts and locations

Locations

  • Associated Medical Professionals of NY

    Syracuse, New York, 13210, United States

  • Beth Israel Deaconness Medical Center

    Boston, Massachusetts, 02115, United States

  • Brigham and Women Hospital

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Medical Center

    Milford, Massachusetts, 01757, United States

  • Dana-Farber/Brigham and Women's Cancer Center in Clinical Affiliation with South Shore Hospital

    South Weymouth, Massachusetts, 02190, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • NYU Long Island

    Garden City, New York, 11530, United States

  • Stamford Hospital

    Stamford, Connecticut, 06904, United States

  • Washington University School of Medicine in St. Louis

    St Louis, Missouri, 63108, United States

  • XCancer Omaha / Urology Cancer Center

    Omaha, Nebraska, 68130, United States

Conditions

Explore the condition pages connected to this study.