New hope for brain lining cancer: spinal chemotherapy after targeted drug failure

NCT ID NCT06296745

First seen Feb 01, 2026 · Last updated May 15, 2026 · Updated 19 times

Summary

This study tests a chemotherapy drug called pemetrexed, given directly into the spinal fluid, for people with a specific type of lung cancer that has spread to the lining of the brain and spinal cord. The cancer has stopped responding to a higher dose of a targeted therapy. The goal is to see if this treatment is safe and can control the disease. About 36 adults aged 18 to 75 with this condition will take part.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Affiliated Huizhou Hospital, Guangzhou Medical University

    RECRUITING

    Huizhou, Guangdong, 516000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.