New hope for brain lining cancer: spinal tap chemo after targeted drug fails
NCT ID NCT06296745
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a chemotherapy drug called pemetrexed, given directly into the spinal fluid, for people with a specific type of lung cancer that has spread to the lining of the brain and spinal cord. The cancer must have gotten worse even after taking a high dose of a targeted therapy like osimertinib. The goal is to see if this treatment is safe and can control the cancer in the brain lining.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Affiliated Huizhou Hospital, Guangzhou Medical University
RECRUITINGHuizhou, Guangdong, 516000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Triple therapy targets tough brain metastases in lung cancer
- New hope for lung cancer patients with brain-spread disease
- New hope for lung cancer patients with brain spread: targeted pill under study