Could a One-Time spinal shot ease pain after lung surgery?
NCT ID NCT05351229
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a single injection of morphine into the spinal fluid can reduce pain and the need for other painkillers after video-assisted or robotic lung surgery. About 90 adults undergoing elective lung surgery will be randomly assigned to receive either the morphine injection or a placebo (salt water). Neither the patient nor the doctor will know which they received. The goal is to find a better way to manage post-surgery pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
morphine sulfate
What this could lead to
If it works, this could offer a simple, single-dose method to better control pain after lung surgery and reduce the need for other painkillers.
What could go wrong
This is a small, early-phase trial (90 people) testing a well-known drug for a new use. The effect may be small or not better than placebo, and morphine carries risks like nausea, itching, or breathing problems.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••