Nasal spray could take the ouch out of ER stitches
NCT ID NCT06284473
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a ketamine nasal spray, given alongside standard numbing medicine, can lower pain during minor procedures like stitching cuts or draining abscesses in the emergency department. About 108 adults and children (ages 7 to under 70) will be randomly assigned to receive either ketamine or a saline placebo spray. Researchers will compare pain scores and monitor for side effects like agitation or drowsiness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketamine
What this could lead to
If it works, this could offer a safe, non-addictive way to ease pain during minor emergency procedures without strong opioids.
What could go wrong
This is a small, early-phase trial (108 people) testing a single dose. Ketamine may cause side effects like dizziness or agitation, and the placebo group also receives standard anesthesia, so the added benefit may be small.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Loyola University Medical Center
RECRUITINGMaywood, Illinois, 60153, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••