Could a nasal spray help Parkinson's? new trial tests insulin and glutathione combo
NCT ID NCT05266417
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial is testing whether a nasal spray containing insulin and glutathione can safely improve symptoms in people with Parkinson's disease. About 56 participants will receive either the active spray or a placebo, added to their usual medications. The study focuses on changes in thinking (verbal fluency) and movement (timed walking, UPDRS scores).
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intranasal insulin and glutathione
What this could lead to
If it works, this could point toward a new add-on treatment to help manage Parkinson's symptoms, potentially improving thinking and movement.
What could go wrong
This is a small, early-phase trial (56 people) testing safety and effectiveness. The treatment may not work better than placebo, and results may not apply to all Parkinson's patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Institute for Neuroimmune Medicine
RECRUITINGDavie, Florida, 33314, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Las Mercedes Medical Research
RECRUITINGHialeah, Florida, 33012, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NextGen Research Group
RECRUITINGMiami, Florida, 33165, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••