Heart failure nasal spray trial pulled before it began
NCT ID NCT07375212
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aimed to see if a single dose of bumetanide given as a nasal spray could quickly lower blood pressure in the lungs and reduce blood volume in people with heart failure. Participants would have had a heart monitor implanted. However, the trial was withdrawn before enrolling anyone, so no results are available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bumetanide (intranasal)
What this could lead to
If it works, this could point toward a convenient, non-injectable way to manage fluid overload in heart failure patients at home.
What could go wrong
This trial was withdrawn before enrolling anyone, so no data exist. Even if run, it was a small pilot study with a single dose, so results would be very preliminary and may not lead to a practical treatment.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Prisma Health
Greenville, South Carolina, 29605, United States