Inhaled virus takes on lung tumors in new trial
NCT ID NCT06228326
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests an inhaled treatment called KB707, a modified herpes virus designed to trigger the immune system against lung tumors. It is for adults with advanced solid tumors that have spread to the lungs and who have run out of standard options. The trial will test KB707 alone and in combination with Keytruda or chemotherapy to see if it is safe and can shrink tumors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
genetically modified herpes simplex virus (KB707)
What this could lead to
If successful, this could offer a new inhaled treatment option for people with advanced lung cancers that have stopped responding to standard therapies.
What could go wrong
This is an early-phase trial (Phase 1/2) with a small number of participants, so safety and effectiveness are not yet proven. The virus-based therapy may cause side effects or fail to shrink tumors.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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BRCR Global
RECRUITINGWeston, Florida, 33326, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-••••
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Emad Ibrahim MD Inc
RECRUITINGRedlands, California, 92373, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Gabrail Cancer Center Research
RECRUITINGCanton, Ohio, 44718, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Henry Ford Health
RECRUITINGDetroit, Michigan, 48202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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HonorHealth Research Institute
RECRUITINGScottsdale, Arizona, 85258, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-••••
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IU Simon Comprehensive Cancer Center
TERMINATEDIndianapolis, Indiana, 46202, United States
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Ochsner/MD Anderson Cancer Center
RECRUITINGNew Orleans, Louisiana, 70121, United States
Contact Phone: •••-•••-••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Precision NextGen Oncology
RECRUITINGBeverly Hills, California, 90212, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Renovatio Clinical
TERMINATEDEl Paso, Texas, 79915, United States
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Renovatio Clinical
TERMINATEDThe Woodlands, Texas, 77380, United States
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Sarah Cannon Research Institute
RECRUITINGNasville, Tennessee, 37203, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UPMC Hillman Cancer Center
TERMINATEDPittsburgh, Pennsylvania, 15232, United States
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XCancer Research Network/Dothan Hematology & Oncology
RECRUITINGDothan, Alabama, 36303, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••