New drug shows promise for boosting growth in kids with dwarfism

NCT ID NCT06164951

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a daily oral drug called infigratinib in 114 children aged 3 to 18 with achondroplasia, the most common form of dwarfism. The goal was to see if it could safely increase their growth rate compared to a placebo. The trial is now complete, and results will show whether this drug can become a new treatment option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Infigratinib (a daily oral drug)

What this could lead to

If it works, this could become a new treatment to help children with achondroplasia grow taller.

What could go wrong

This is a completed Phase 3 trial, but results are not yet public. The drug may not work better than placebo, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

achondroplasia bone disorder Dwarfism hereditary disease Mucopolysaccharidosis IV musculoskeletal system disorder osteochondrodysplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • QED Investigative Site

    San Francisco, California, 94609, United States

  • QED Investigative Site

    Aurora, Colorado, 80045, United States

  • QED Investigative Site

    Baltimore, Maryland, 21287, United States

  • QED Investigative Site

    Columbia, Missouri, 65212, United States

  • QED Investigative Site

    Cincinnati, Ohio, 45229, United States

  • QED Investigative Site

    Nashville, Tennessee, 37232, United States

  • QED Investigative Site

    Madison, Wisconsin, 53792, United States

  • QED Investigative Site

    Buenos Aires, Buenos Aires F.D., C1245AAM, Argentina

  • QED Investigative Site

    Parkville, Victoria, 3052, Australia

  • QED Investigative Site

    Edmonton, Alberta, T6G 2B7, Canada

  • QED Investigative Site

    London, Ontario, N6A 5W9, Canada

  • QED Investigative Site

    Ottawa, Ontario, K1H 8L1, Canada

  • QED Investigative Site

    Montreal, Quebec, H3T 1C5, Canada

  • QED Investigative Site

    Bron, 69677, France

  • QED Investigative Site

    Paris, 75015, France

  • QED Investigative Site

    Toulouse, 31059, France

  • QED Investigative Site

    Rome, 00168, Italy

  • QED Investigative Site

    Bergen, 5009, Norway

  • QED Investigative Site

    Oslo, 0372, Norway

  • QED Investigative Site

    Singapore, 229899, Singapore

  • QED Investigative Site

    Málaga, 29010, Spain

  • QED Investigative Site

    Vitoria-Gasteiz, 01008, Spain

  • QED Investigative Site

    Bristol, BS2 8BJ, United Kingdom

  • QED Investigative Site

    Glasgow, G51 4TF, United Kingdom

  • QED Investigative Site

    London, SE1 7EH, United Kingdom

  • QED Investigative Site

    Manchester, M13 9WL, United Kingdom

  • QED Investigative Site

    Sheffield, S10 2TH, United Kingdom