Can growth hormone boost height in children with dwarfism?
NCT ID NCT05353192
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial is testing whether daily injections of recombinant human growth hormone can improve growth in children with achondroplasia, a genetic condition that causes short stature. The study will include children aged 2 to 10 who have not previously been treated with growth hormone. Over 52 weeks, researchers will measure changes in growth rate and height to see if the treatment is effective and safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Recombinant human growth hormone
- What this could lead to
- If effective, this could offer a way to increase growth and height in children with achondroplasia, potentially improving their quality of life.
- What could go wrong
- This is a small, single-arm study without a placebo group, so results may be less reliable. Growth hormone may not significantly improve height and could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Children's Hospital of Fudan University
Shanghai, Shanghai Municipality, 201102, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a weekly shot help children with achondroplasia grow taller?
- Weekly shot may boost growth in kids with dwarfism
- Experimental achondroplasia drug trial halted early
- No treatment, just tracking: PROPEL study watches how kids with achondroplasia grow
- New drug aims to boost height in kids with dwarfism
- New registry aims to unlock secrets of bone disorder