Experimental achondroplasia drug trial halted early

NCT ID NCT06067425

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested an experimental drug called SAR442501 in children with achondroplasia, a common form of dwarfism. The goal was to see if the drug was safe and could improve growth. However, the trial was stopped early after enrolling only 16 children, so we have very little information about how well it worked.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SAR442501 (an experimental drug given as a shot under the skin)

What this could lead to

If successful, this drug could help children with achondroplasia grow more, potentially reducing some health complications.

What could go wrong

The trial was terminated early with only 16 participants, so results are very limited. It is unclear if the drug is safe or effective, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

achondroplasia osteochondrodysplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site Number : 0360001

    Parkville, Victoria, 3052, Australia

  • Investigational Site Number : 1560001

    Wuhan, 430030, China

  • Investigational Site Number : 1560002

    Shanghai, 200120, China

  • Investigational Site Number : 3800001

    Rome, Roma, 00168, Italy

  • Investigational Site Number : 3800002

    Milan, Lombardy, 20122, Italy

  • Investigational Site Number : 4100001

    Seoul, Seoul-teukbyeolsi, 03080, South Korea

  • Investigational Site Number : 4100002

    Seoul, Seoul-teukbyeolsi, 06351, South Korea

  • Investigational Site Number : 7240001

    Esplugues de Llobregat, Catalunya [Cataluña], 08950, Spain

  • Investigational Site Number : 7240002

    Vitoria-Gasteiz, Basque Country, 01008, Spain