Less dialysis, more kidney? study tests gentler start for kidney failure patients
NCT ID NCT03418181
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This study tests whether starting haemodialysis with fewer sessions per week (twice instead of the standard three times) can help preserve patients' remaining natural kidney function. New dialysis patients who still have some kidney function are randomly assigned to either standard thrice-weekly dialysis or an incremental approach that adjusts dialysis dose based on their natural kidney function. The goal is to see if this gentler start is feasible and whether it slows the loss of native kidney function, which could improve quality of life and survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- incremental haemodialysis (starting with twice-weekly sessions, adjusted based on remaining kidney function)
- What this could lead to
- If successful, this approach could help new dialysis patients preserve their natural kidney function longer, potentially reducing dietary restrictions and improving survival.
- What could go wrong
- This is a small feasibility study, not designed to prove effectiveness. The benefits of incremental dialysis are uncertain, and some patients may need more frequent sessions to manage fluid or electrolyte imbalances.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DIALYSIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
East and North Hertfordshire NHS Trust (incorporating Mount Vernon Cancer Centre)
Stevenage, SG1 4AB, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Virtual nature escape could calm dialysis patients
- Could a diabetes drug shield heart transplant patients from kidney failure?
- Heat pack before dialysis needle may ease pain, study tests best timing
- Diabetes drug semaglutide tested in dialysis patients for safety
- Obesity blocks kidney transplants: new study investigates why
- Kidney transplant drug showdown: which regimen saves more function?