Buspirone tested to boost breathing in spinal cord injury patients
NCT ID NCT05041322
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This phase 2 trial tested whether buspirone, a drug usually used for anxiety, can improve breathing capacity in people with chronic high-level spinal cord injuries. Thirteen participants took either buspirone or a placebo for 14 days. Researchers measured lung function, breathing drive, sleep quality, and exercise capacity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
buspirone (BuSpar)
What this could lead to
If it works, this could point toward a medication that helps people with spinal cord injuries breathe more easily.
What could go wrong
This is a very small, early-phase trial with only 13 participants. The results may not apply to everyone, and the drug may not improve breathing enough to be noticeable.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SPINAL CORD INJURIES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Spaulding Hospital Cambridge
Cambridge, Massachusetts, 02138, United States