New heart pump may reduce death and stroke in risky surgeries

NCT ID NCT05756751

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests the Impella 5.5 heart pump in 123 high-risk patients with weak hearts (ejection fraction 25% or less) who need complex cardiac surgery. The pump supports the heart during and after surgery to prevent failure, stroke, and other complications. The goal is to confirm the device's safety and effectiveness in real-world use.

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Conditions

The condition(s) this trial relates to.

left ventricular failure Ventricular Dysfunction, Left

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Deutsches Herzzentrum der Charité

    Berlin, 13353, Germany

  • IKEM Prague

    Prague, 14021, Czechia

  • Krankenhaus der Barmherzigen Brüder Trier

    Trier, 54292, Germany

  • Medizinische Hochschule Hannover

    Hanover, 30625, Germany

  • RWTH Uniklinik Aachen - Klinik für Herzchirurgie

    Aachen, North Rhine-Westphalia, 52074, Germany

  • UKSH Campus Kiel - Klinik für Herz- und Gefäßchirurgie

    Kiel, Schleswig-Holstein, 24105, Germany

  • Universitäres Herz- und Gefäßzentrum Hamburg - Klinik und Poliklinik für Herz- und Gefäßchirurgie

    Hamburg, 20246, Germany

  • Universitätsklinikum Düsseldorf, Klinik für Herzchirurgie

    Düsseldorf, North Rhine-Westphalia, 40225, Germany

  • Universitätsklinikum Giessen

    Giessen, 35392, Germany

  • Universitätsklinikum Heidelberg - Klinik für Herzchirurgie

    Heidelberg, Baden-Wurttemberg, 69120, Germany

  • Universitätsmedizin Essen, Westdeutsches Herzzentrum, Klinik für Thorax- und Kardiovaskuläre Medizin

    Essen, North Rhine-Westphalia, 45147, Germany

  • Universitätsmedizin Halle/Saale - Klinik für Herzchirurgie

    Halle, SA, 06120, Germany

  • Universitätsmedizin Mainz, Klinik und Poliklinik für Herz- und Gefäßchirurgie

    Mainz, RLP, 55131, Germany