Heart pump may boost survival in High-Risk surgery patients

NCT ID NCT05529654

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether using the Impella 5.5 heart pump during and after heart surgery improves outcomes for 100 patients with severely weakened hearts. The pump supports blood flow, aiming to reduce death, stroke, kidney failure, and heart failure after surgery. Participants must be stable enough for specific heart procedures like bypass or valve repair.

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Conditions

The condition(s) this trial relates to.

left ventricular failure Ventricular Dysfunction, Left

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Barnes-Jewish Hospital

    St Louis, Missouri, 63110, United States

  • Baylor Scott and White - Plano

    Plano, Texas, 75093, United States

  • Brigham & Women's

    Boston, Massachusetts, 02115, United States

  • Cardiology Associates Research Group

    Jonesboro, Arkansas, 72401, United States

  • Centennial Heart Cardiovascular

    Nashville, Tennessee, 37203, United States

  • Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • Emory University Hospital

    Atlanta, Georgia, 30322, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Hospital of The University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Keck School of Medicine

    Los Angeles, California, 90033, United States

  • Mass General Hospital

    Boston, Massachusetts, 02114, United States

  • Minneapolis Heart Institute Foundation/Abbott Northwestern Hospital

    Minneapolis, Minnesota, 55407, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • NCH Rooney Heart Institute

    Naples, Florida, 34102, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • New Hanover Regional Medical Center

    Wilmington, North Carolina, 28401, United States

  • New York- Presbyterian Hospital/ Columbia University Medical Center

    New York, New York, 10032, United States

  • Providence St. Vincent Medical Center

    Portland, Oregon, 97225, United States

  • Tri-City Medical Center

    San Diego, California, 92056, United States

  • University of Texas Austin Dell Medical School/Ascension Texas

    Austin, Texas, 78705, United States