New study tests tools to help families share cancer genetic results

NCT ID NCT04763915

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 31 times

Summary

The IMPACT Study is testing two web-based tools—GeneSHARE and LivingLabReport—to help people with inherited cancer gene variants share their genetic test results with family members and follow cancer screening guidelines. The study involves 720 adults with certain inherited cancer syndromes or variants of uncertain significance. Researchers will measure changes in family communication and adherence to recommended cancer risk management over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Vanderbilt-Ingram Cancer Center

    Nashville, Tennessee, 37212, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GeneSHARE web-based toolkit and LivingLabReport website

What this could lead to

If successful, this could lead to better ways for people with inherited cancer risks to inform their relatives and follow recommended screenings.

What could go wrong

This is an observational study testing behavioral tools, not a treatment. Results may not apply to everyone, and improvements in communication may not directly reduce cancer rates.

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm colorectal cancer colorectal neoplasm endometrial cancer endometrium neoplasm hereditary neoplastic syndrome prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.