New spinal fluid treatment targets deadly cancer spread
NCT ID NCT06462222
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new treatment for leptomeningeal metastasis, a condition where cancer spreads to the lining of the brain and spinal cord. The treatment combines an immune checkpoint inhibitor (a drug that helps the immune system fight cancer) with pemetrexed (a chemotherapy drug), both injected directly into the spinal fluid. The study involves 45 adults with solid tumors and aims to find the safest dose and check for side effects.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beijing Chest Hospital, Capital Medical University
Beijing, 101100, China
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Cancer Center, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine
Beijing, China
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Huizhou First Hospital Affiliated to Guangdong Medical University
Huizhou, Guangdong, China
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The Affiliated Huizhou Hospital, Guangzhou Medical University
Huizhou, Guangdong, 516000, China