Alzheimer's risk info: does knowing help or hurt latinos?

NCT ID NCT04471779

Completed Knowledge-focused Sponsor: Columbia University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how giving people information about their genetic risk for Alzheimer's disease affects them emotionally and behaviorally. It involved 374 Latino adults aged 40-64 in New York City who did not have Alzheimer's. Some participants learned their risk based only on ethnicity and family history, while others also got results from a genetic test (APOE). Researchers then tracked their distress, memory, and health habits over 15 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Disclosure of APOE genotype (genetic risk information)
What this could lead to: If successful, this could help doctors understand the best way to share Alzheimer's risk information with Latino communities, potentially reducing distress and promoting healthy behaviors.
What could go wrong: This is a completed observational study, not a treatment trial. It does not test a drug or cure, so it cannot directly lead to a new therapy. The results may not apply to other ethnic groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE

Contacts and locations

Locations

Columbia University Irving Medical Center

New York, New York, 10032, United States

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