Could induced hypothermia save brains after stubborn seizures?

NCT ID NCT07383779

Not yet recruiting Disease control Sponsor: Versailles Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether lowering body temperature to about 91°F for 24 hours improves brain recovery in adults with severe seizures that don't stop with standard medicines. About 466 people on breathing machines will be randomly assigned to cooling or normal temperature care. The goal is to see if cooling reduces brain damage and seizure activity within 90 days.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CONVULSIVE REFRACTORY STATUS EPILEPTICUS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

new-onset refractory status epilepticus Status Epilepticus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONVULSIVE REFRACTORY STATUS EPILEPTICUS STATUS EPILEPTICUS

Contacts and locations

Locations

CH Annecy Genevois

Metz-Tessy, France
CH Le Mans

Le Mans, France
CH Melun-Sénart

Melun, France
CH Simone Veil

Cannes, France
CH Sud Francilien

Corbeil-Essonnes, France
CH Versailles

Le Chesnay, France
CHITS Toulon

Toulon, France
CHR Orléans

Orléans, France
CHU Brest

Brest, France
CHU Dijon

Dijon, France
CHU Nantes

Nantes, France
CHU Rennes

Rennes, France
GH Paris Saint-Joseph

Paris, France
Hôpital Ambroise Paré

Boulogne-Billancourt, France
Hôpital COCHIN

Paris, France
Hôpital Edouard Herriot

Lyon, France
Hôpital Foch

Suresnes, France
Hôpital Hautepierre

Strasbourg, France
Hôpital Louis Mourier

Colombes, France
Hôpital de la Croix-Rousse

Lyon, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.