Kidney function may change how diabetes drug works

NCT ID NCT06246175

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how the body processes HRS9531, an experimental diabetes drug, in people with different levels of kidney function. Researchers gave a single dose to 32 volunteers—some with healthy kidneys and some with mild impairment—and measured drug levels over time. The goal is to understand if kidney problems affect how the drug is absorbed and cleared, which could guide future dosing recommendations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HRS9531 injection

What this could lead to

If successful, this study could help doctors determine the right dose of HRS9531 for people with kidney problems, making treatment safer and more effective.

What could go wrong

This is a very early, small study (32 people) focused on drug levels, not on treating diabetes. It won't show if HRS9531 actually works for the disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chengdu Xinhua Hospital

    Chengdu, Sichuan, 610000, China