Shock therapy at home? new trial tests brain zaps for speech loss

NCT ID NCT07260253

Recruiting now Symptom relief Sponsor: Maya Henry Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study tests whether combining home-based brain stimulation (tDCS) with virtual speech therapy can improve communication in adults with primary progressive aphasia, a language disorder often caused by Alzheimer's disease. Eighty participants will receive either active or placebo stimulation during speech therapy sessions. Researchers will measure changes in naming ability and communication confidence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial direct current stimulation (tDCS)
What this could lead to: If it works, this could point toward a practical, home-based treatment to help people with primary progressive aphasia communicate better.
What could go wrong: This is an early-stage study with only 80 participants, so results may not apply to everyone. The treatment may not improve communication more than speech therapy alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease aphasia communication disorder logopenic progressive aphasia primary progressive aphasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOGOPENIC PROGRESSIVE APHASIA (LPA) LOGOPENIC VARIANT OF PRIMARY PROGRESSIVE APHASIA (LPA) LOGOPENIC VARIANT PRIMARY PROGRESSIVE APHASIA PRIMARY PROGRESSIVE APHASIA(PPA) PROGRESSIVE APHASIA PROGRESSIVE APHASIA IN ALZHEIMER'S DISEASE

Contacts and locations

Locations

UCSF Memory and Aging Cener
RECRUITING

San Francisco, California, 94158, United States
University of Texas
RECRUITING

Austin, Texas, 78712, United States

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