Shock therapy at home? new trial tests brain zaps for speech loss
NCT ID NCT07260253
First seen Jan 11, 2026 · Last updated Jun 20, 2026 · Updated 24 times
Summary
This study tests whether combining home-based brain stimulation (tDCS) with virtual speech therapy can improve communication in adults with primary progressive aphasia, a language disorder often caused by Alzheimer's disease. Eighty participants will receive either active or placebo stimulation during speech therapy sessions. Researchers will measure changes in naming ability and communication confidence.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UCSF Memory and Aging Cener
RECRUITINGSan Francisco, California, 94158, United States
Contact
Contact Email: •••••@•••••
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University of Texas
RECRUITINGAustin, Texas, 78712, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If it works, this could point toward a practical, home-based treatment to help people with primary progressive aphasia communicate better.
What could go wrong
This is an early-stage study with only 80 participants, so results may not apply to everyone. The treatment may not improve communication more than speech therapy alone.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.