New Wound-Cleaning method may let surgeons close incisions right away after severe appendicitis
NCT ID NCT07688109
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This trial tests whether closing the surgical wound immediately after cleaning it with a special high-pressure irrigation technique (HIEDI) is as good as or better than waiting a few days to close it. The study involves 200 people aged 12 and older who have open surgery for complicated appendicitis (where the appendix has burst or become gangrenous). Researchers will compare infection rates, healing, hospital stay length, and patient satisfaction over 30 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- High-Efficiency Incision and Drainage with Irrigation (HIEDI) technique
- What this could lead to
- If primary closure with HIEDI works as well as delayed closure, patients could avoid a second surgery and have shorter hospital stays.
- What could go wrong
- This is a single-center study in a resource-limited setting, so results may not apply elsewhere. Infection rates could still be higher with immediate closure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Al-Gumhori Teaching Hospital
Sanaa, Yemen
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Al-Kuwaint University Hospital
Sanaa, Yemen
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Al-Thawra Modern General Hospital
Sanaa, Yemen
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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