Spinal anesthesia studied in heart valve surgery patients

NCT ID NCT06156592

Completed Knowledge-focused Sponsor: University of Manitoba Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how spinal anesthesia changes blood flow and heart function in 44 patients with severe aortic stenosis or mitral regurgitation during valve replacement surgery. Researchers measured the need for drugs that support blood pressure and heart function, as well as heart performance on ultrasound. The goal was to compare these effects between the two heart valve conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: high spinal anesthesia (bupivacaine, fentanyl, epimorphine)
What this could lead to: If successful, this could help doctors choose safer anesthesia methods for heart valve surgery patients.
What could go wrong: This is a small, completed observational study, not a treatment trial. Results may not apply to all patients or change current practice.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis mitral valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEVERE AORTIC VALVE STENOSIS SEVERE MITRAL VALVE REGURGITATION

Contacts and locations

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Locations

Department of Anesthesiology, Perioperative and Pain Medicine, SBGH

Winnipeg, Manitoba, R2H 2A6, Canada

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