Heart SCORE study aims to crack the code on heart disease disparities

NCT ID NCT00143923

Ongoing Knowledge-focused Sponsor: University of Pittsburgh Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 11, 2026 · Updated 3 times

Summary

This study follows 2,000 adults aged 45-75 in Pennsylvania to better understand why some groups have higher heart disease risk. About 800 participants at higher risk will receive either usual care or a personalized program with nutrition, exercise, and stress management advice. The goal is to see if such lifestyle support can reduce heart attacks and strokes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lifestyle counseling (nutrition, exercise, stress management)
What this could lead to: If successful, this could show that personalized lifestyle programs effectively lower heart disease risk in high-risk populations.
What could go wrong: This is an observational study with a small randomized part, so results may not apply broadly. Lifestyle changes are hard to maintain long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASES

Contacts and locations

Locations

University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States

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