Heart pacing mimics exercise to boost weak hearts

NCT ID NCT06332391

Recruiting now Knowledge-focused Sponsor: Denice Hodgson-Zingman, MD Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether pacing the heart to mimic the speed of a workout can improve heart function in people with heart failure. Fifty-two adults with a weak heart and an implanted defibrillator will receive either active pacing or a sham (fake) pacing for 6 weeks. Researchers will measure changes in heart pumping strength, symptoms, and quality of life to see if this approach could become a new therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Exercise-similar cardiac pacing via implanted defibrillator
What this could lead to: If it works, this could point toward a drug-free way to strengthen the heart in people with heart failure.
What could go wrong: This is a small, early-phase study testing a concept, not a proven treatment. The pacing may not improve heart function or quality of life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure Motor Activity systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE, SYSTOLIC

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

University of Iowa Hospitals and Clinics
RECRUITING

Iowa City, Iowa, 52242, United States

Contact Phone: •••-•••-••••

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

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