Drug cocktail aims to ease dual Heart-Lung strain

NCT ID NCT07147114

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 18 times

Summary

This study tests whether adding macitentan to standard dapagliflozin treatment helps people with heart failure and a specific type of lung hypertension. About 64 adults in South Korea will take either the combo or dapagliflozin alone for 24 weeks. Researchers will measure changes in lung blood pressure, heart strain, walking ability, and quality of life.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

  • Chonnam National University Hospital

    RECRUITING

    Gwangju, 61469, South Korea

  • Chungbuk National University Hospital

    NOT_YET_RECRUITING

    Chungju, 28644, South Korea

  • Chungnam National University Hospital

    RECRUITING

    Daejeon, 35015, South Korea

  • Gachon University Gil Hospital

    RECRUITING

    Incheon, 405-760, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Incheon Sejong Hospital

    NOT_YET_RECRUITING

    Incheon, 21080, South Korea

  • Keimyung University Dongsan Hospital

    RECRUITING

    Daegu, 42601, South Korea

  • Koera University Guro Hospital

    NOT_YET_RECRUITING

    Seoul, 08308, South Korea

  • Pusan National University Hospital

    RECRUITING

    Busan, 49241, South Korea

  • Pusan National University Yangsan Hospital

    NOT_YET_RECRUITING

    Yangsan, 50612, South Korea

  • Samsung Medical Center

    NOT_YET_RECRUITING

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • The Catholic University of Korea, Seoul St.Mary

    RECRUITING

    Seoul, 06591, South Korea

  • Yonsei University Health System, Severance Hospital

    NOT_YET_RECRUITING

    Seoul, 03722, South Korea

  • Yonsei University, Wonju Severance Christian Hospital

    RECRUITING

    Wŏnju, 26426, South Korea

Conditions

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