Biomarker-Guided trial aims to find best chemo for head and neck cancer

NCT ID NCT02128906

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests which chemotherapy combination works better when given with radiation for advanced head and neck cancer. About 120 adults with stage III or IV disease will receive either cisplatin or a mix of docetaxel and cetuximab. Researchers will also check if a tumor marker called ERCC1 helps predict which treatment is best.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma laryngeal disorder squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Hillman Cancer Center - Radiation Oncology

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••