Stomach bug treatment in teens could stop cancer before it starts

NCT ID NCT05926804

Recruiting now Disease control Sponsor: Miguel O'Ryan Gallardo Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a 'screen and treat' approach for H. pylori infection in 14-18 year olds in Chile, where stomach cancer rates are high. Researchers will screen up to 1000 teens and randomly assign 210 persistently infected participants to receive antibiotics or no treatment. They aim to see if eradication reduces signs of stomach damage and changes gut bacteria, with the goal of preventing future cancer.

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Conditions

The condition(s) this trial relates to.

Helicobacter pylori infectious disease gastric cancer prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HELICOBACTER PYLORI INFECTION

Contacts and locations

Locations

Universidad de Aysén
RECRUITING

Coyhaique, Chile
Universidad de Chile
RECRUITING

Santiago, Chile
Universidad de la Frontera
RECRUITING

Temuco, Chile

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