Scientists hunt for friendly viruses to tame IBD
NCT ID NCT07240181
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at the viruses (called bacteriophages) living in the guts of people with inflammatory bowel disease (IBD) and healthy people. Researchers want to understand how these viruses differ and whether they can be grown in a lab to create a new treatment. The study involves 40 adults (30 with IBD and 10 healthy donors) and only collects stool and blood samples — no treatments are given.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Dec 2025
An estimate. Start dates often move.
- Expected to finish
-
Dec 2029
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study is a non-interventional trial aiming to examine the virome/bacteriophages from stool samples of patients with IBD (UC, CD, and PSC-IBD) and compare these with healthy controls (fecal donors). Study participants The study will include 30 patients with IBD: 10 with ulcerative colitis (UC), 10 with Crohn's disease (CD), and 10 with PSC-IBD. In each subgroup, 5 participants with active disease and 5 in remission will be included (active disease is defined as fecal calprotectin \> 250). In addition, 10 fecal donors will be included as healthy controls.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria for patients: * Confirmed diagnosis of UC, CD, or PSC-IBD for at least 6 months * Age ≥ 18 years * Stable medical treatment for IBD (and PSC-IBD) within the past 3 months * Stable lifestyle within the past month (including diet, exercise, and sleep habits) * Verbal and written informed consent Exclusion criteria for patients: * Use of antibiotics within the past 3 months * Pregnancy or breastfeeding * Substance abuse or excessive alcohol consumption (according to Danish Health Authority guidelines) * Other known comorbidities that may affect the gut microbiome (e.g., type 1 diabetes, other autoimmune diseases, cancer, severe obesity, etc.)
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Colitis ulcerative are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Hvidovre Hospital
Hvidovre, 2650, Denmark
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Triple-Pronged attack on gut inflammation put to the test
- Can a new pill tame inflammatory bowel disease?
- A breath of fresh air? stool 'Fingerprint' may predict IBD Flare-Ups
- Could a 15-Minute ultrasound replace the scope for IBD monitoring?
- Can a new injection plus a pill tame ulcerative colitis?
- A simple hospital checklist could flag hidden malnutrition in kids with IBD